Keith Roizman, Founder, Executive Chairman and Chief Technology Officer
Mr. Roizman is patient advocate, and entrepreneur in the field of retinal science and medicine since he was diagnosed with a retinal degenerative eye disorder in 1991. Roizman was Founder, President and Chief Executive Officer of Photogenesis, Inc., the first company in the world to perform a 10-patient clinical study using intact retinal cell layers of both retinal pigment epithelial and photoreceptor cells from adult human donor eyes for the treatment of age-related macular degeneration (AMD) and retinitis pigmentosa (RP). Under Mr. Roizman’s leadership, Photogenesis acquired and/or developed the intellectual property and platform technology that is the foundation for the way all forms of stem-cell-derived retinal cell layers are being used in current treatments for retinal eye diseases. Mr. Roizman is the inventor and/or co-inventor for Macregen’s intellectual property, including the Company’s platform technology, Ophthamize™, using cell-penetrating peptides in combination with numerous drugs to potentially treat a broad spectrum of eye diseases. Roizman identified the opportunity for MacRegen’s lead drug candidate, Mitia™, which has significant potential as a disease-modifying drug for the treatment of all forms of AMD.
Since Mr. Roizman became involved in the field of retinal science and medicine, he has been responsible for raising many millions of dollars as an entrepreneur as well as for several prominent academic research institutions. Prior to Mr. Roizman being diagnosed with RP, he had a successful career as an architectural designer, master planner and inovator for a number of the largest high-technology civic structures around the world which were valued in the many billions of dollars. Included among these works were the master plans and buildings for Market Street East in Philadelphia, Melbourne Park and Rod Laver Arena in Melbourne, the new Parliament House and Capitol in Canberra, and Darling Harbor Master Plan and Exhibition Center in Sydney, Australia. Mr. Roizman is a proud alumnus of Temple University where he attended both the Schools of Architecture and Engineering in Philadelphia, as well as the Tyler School of Art in Rome, Italy. Roizman is an auto-didact, futurist and an anticipatory design scientist and inventor in numerous disciplines.